General Selection Criteria

General Criteria/Indications

• Adults age 18 to 55,  >55 on a case-by-case basis.
• Diabetes Mellitus Type I (insulin dependent).
• Chronic renal failure secondary to Diabetic Nephropathy.
• Ability to be compliant with medical regimen.
• Ability to understand risks and benefits of procedure.
• Brittle diabetics not controlled by exogenous insulin therapy (pancreas transplant alone).
• Ability to withstand the surgery and immunosuppression.
• Absence of contraindications.
  

Contraindications for Kidney/Pancreas Transplantation

• Insufficient cardiac reserve:
  *non-correctable coronary artery disease.
  *ejection fraction <40%.
  *recent myocardial infarction.
• Extensive peripheral vascular disease.
• Lack of well-defined secondary complications.
• Ongoing substance abuse.   
• Debilitating psychiatric illness.
• Significant obesity (body weight >100 kgs).